Dolan 2003.

Methods	Two group, open, randomised controlled trial. Randomisation: in blocks of ten by randomly drawing cards from an envelope. List of case numbers and group allocation not known to researcher or trial nurse. Follow up for four months.
Participants	Geographic region: Australia Study setting: Prison. Participants were inmates on a waiting list for MMT. n = 382 males mean age = 27 years Eligibility criteria: heroin problem confirmed by medical interview, serving sentences of more than four months, and able to provide informed consent.
Interventions	Treatment: methadone maintenance treatment ‐ flexible dose (mean 61mg, range 1‐180mg). Control: wait‐list.
Outcomes	Heroin use ‐ Hair analysis and self report. Syringe sharing. HIV and HCV seroprevalence.
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	Low risk	Drawing lots.
Allocation concealment?	Low risk	A‐Adequate. Central allocation.
Incomplete outcome data addressed? All outcomes	Low risk	Missing outcome information balanced between groups. 191 randomised to each group, 124 and 129 followed up in each group.
Free of other bias?	Low risk	Baseline characteristics similar.