Table 1.
Homozygote or heterozygote frequencies of the CLEC4M polymorphism in samples from northern China
| VNTR polymorphisma | |||
|---|---|---|---|
| Heterozygotes | Homozygotes | ||
| Beijing community population | |||
| All cases (n = 339) | 139 (41.0%) | 200 (59.0%) | |
| Random controls (n = 227) | 110 (48.5%) | 117 (51.5%) | |
| OR (95% c.i.) | 1.29 (0.89–1.87) | ||
| P value | 0.19 | ||
| Cases with comorbid conditions (n = 52) | 20 (38.5%) | 32 (61.5%) | |
| Random controls (n = 227) | 110 (48.5%) | 117 (51.5%) | |
| OR (95% c.i.) | 1.36 (0.60–3.07) | ||
| P value | 0.46 | ||
| Cases without comorbid conditions (n = 287) | 119 (41.5%) | 168 (58.5%) | |
| Random controls (n = 227) | 110 (48.5%) | 117 (51.5%) | |
| OR (95% c.i.) | 1.26 (0.86–1.85) | ||
| P value | 0.23 | ||
| Severe cases (n = 19) | 8 (42.1%) | 11 (57.9%) | |
| Mild cases (n = 268) | 111 (41.4%) | 157 (58.6%) | |
| OR (95% c.i.) | 1. 00 (0.38–2.59) | ||
| P value | 1. 00 | ||
| Beijing HCW population | |||
| HCW cases (n = 42) | 14 (33.3%) | 28 (66.7%) | |
| HCW controls (n = 40) | 18 (45.0%) | 22 (55.0%) | |
| OR (95% c.i.) | 1.51 (0.58–3.99) | ||
| P value | 0.40 | ||
| Tianjin population | |||
| All cases (n = 60) | 33 (55.0%) | 27 (45.0%) | |
| All controls (n = 129) | 72 (55.8%) | 57 (44.2%) | |
| OR (95% c.i.) | 1.18 (0.60–2.34) | ||
| P value | 0.63 | ||
OR, odds ratio; c.i., confidence interval; VNTR, variable number tandem repeat; HCW, health care worker.
aThe heterozygotes are used as the reference group, and all ORs and P values are adjusted for age and gender. Primer sequences used for genotyping are listed in Supplementary Table 2 online.