Table 2. Sequences, Helical Contents, and Dissociation Constants of Peptides to Gal-3c.
peptide | sequence | helicity | Kd (μM) |
---|---|---|---|
p4-BP | H-GAQECVYKEQSCKSAG-NH2 | 32% | |
p4-flu-BP | H-GAQECVYKEQSCKSAG-GGGK-(flu)-NH2 | 0.45 ± 0.18 | |
(3.75 ± 2.22)a | |||
p8-BP | H-GAQECPPKEPACKKAG-NH2 | 14% | |
p8-flu-BP | H-GAQECPPKEPACKKAG-GGGK-(flu)-NH2 | nd | |
p10-BP | H-GAPECKRKEYECKKAG-NH2 | 30% | |
p10-flu-BP | H-GAPECKRKEYECKKAG-GGGK-(flu)-NH2 | 1.16 ± 0.42 | |
(4.74 ± 3.53)a | |||
control-BP | H-GAAECAAKEAACKAAG-NH2 | 60% | |
control-flu-BP | H-GAAECAAKEAACKAAG-GGGK-(flu)-NH2 | nd | |
p4 | H-GAQECVYKEQSCKSAG-NH2 | nd | |
p4-flu | H-GAQECVYKEQSCKSAG-GGGK-(flu)-NH2 | nd | |
p8 | H-GAQECPPKEPACKKAG-NH2 | nd | |
p8-flu | H-GAQECPPKEPACKKAG-GGGK-(flu)-NH2 | nd | |
p10 | H-GAPECKRKEYECKKAG-NH2 | 5.7% | |
p10-flu | H-GAPECKRKEYECKKAG-GGGK-(flu)-NH2 | nd | |
control | H-GAAECAAKEAACKAAG-NH2 | 3.4% | |
control-flu | H-GAAECAAKEAACKAAG-GGGK-(flu)-NH2 | nd | |
lactose | 1 mMb |