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. 2020 Mar 10;5(11):5666–5674. doi: 10.1021/acsomega.9b03461

Table 2. Sequences, Helical Contents, and Dissociation Constants of Peptides to Gal-3c.

peptide sequence helicity Kd (μM)
p4-BP H-GAQECVYKEQSCKSAG-NH2 32%  
p4-flu-BP H-GAQECVYKEQSCKSAG-GGGK-(flu)-NH2   0.45 ± 0.18
      (3.75 ± 2.22)a
p8-BP H-GAQECPPKEPACKKAG-NH2 14%  
p8-flu-BP H-GAQECPPKEPACKKAG-GGGK-(flu)-NH2   nd
p10-BP H-GAPECKRKEYECKKAG-NH2 30%  
p10-flu-BP H-GAPECKRKEYECKKAG-GGGK-(flu)-NH2   1.16 ± 0.42
      (4.74 ± 3.53)a
control-BP H-GAAECAAKEAACKAAG-NH2 60%  
control-flu-BP H-GAAECAAKEAACKAAG-GGGK-(flu)-NH2   nd
p4 H-GAQECVYKEQSCKSAG-NH2 nd  
p4-flu H-GAQECVYKEQSCKSAG-GGGK-(flu)-NH2   nd
p8 H-GAQECPPKEPACKKAG-NH2 nd  
p8-flu H-GAQECPPKEPACKKAG-GGGK-(flu)-NH2   nd
p10 H-GAPECKRKEYECKKAG-NH2 5.7%  
p10-flu H-GAPECKRKEYECKKAG-GGGK-(flu)-NH2   nd
control H-GAAECAAKEAACKAAG-NH2 3.4%  
control-flu H-GAAECAAKEAACKAAG-GGGK-(flu)-NH2   nd
lactose     1 mMb
a

In the presence of excess lactose (100 mM).

b

Refs (3537).

c

nd: not determined.