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. 2020 Mar 5;11(11):3216–3224. doi: 10.7150/jca.41492

Figure 6.

Figure 6

miR-129-2-3p upregulation impairs ICC tumor growth in vivo. (A) Representative images of tumor xenografts derived from QBC-939 cells transfected with miR-129-2-3p mimics or miR-NC. (B) The volume of tumor xenografts in the miR-129-2-3p mimics group was smaller than that in the miR-NC group. *P<0.05 compared with miR-NC. (C) The tumor xenografts in the miR-129-2-3p mimics and miR-NC group were excited and weighed after four weeks of implantation. **P<0.01 vs. miR-NC. (D) RT-qPCR was performed to analyze miR-129-2-3p expression in the tumor xenografts. **P<0.01 vs. miR-NC. (E) The expression level of Wip1 protein in tumor xenografts was analyzed by western blot analysis. **P<0.01vs. miR-NC.