Table 3.
Univariate and multivariate Cox proportional hazards analysis of overall survival.
| Varies | Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|---|
| HR | 95%CI | P | HR | 95%CI | P | ||
| Age | 1.015 | (1.002- 1.029) | 0.025 | 1.007 | (0.992- 1.022) | 0.358 | |
| BMI | 1.064 | (1.010- 1.120) | 0.019 | 0.953 | (0.897- 1.013) | 0.121 | |
| FIGO (Ⅲ-Ⅳ vs. Ⅰ-Ⅱ) |
7.717 | (4.963- 12.000) | <0.001 | 7.643 | (4.797- 12.175) | <0.001 | |
| Histological subtype (serous vs. others) |
1.904 | (1.292- 2.805) | 0.001 | 1.262 | (0.826- 1.930) | 0.282 | |
| Histological grade (G2-G3 vs. G1) |
4.457 | (2.660- 7.466) | <0.001 | 3.672 | (2.069- 6.517) | <0.001 | |
| Optimal debulking (yes vs. no) |
1.778 | (1.255- 2.520) | 0.001 | 2.662 | (1.804- 3.927) | <0.001 | |
| Malignant ascites (yes vs. no) |
2.350 | (1.650- 3.347) | <0.001 | 1.320 | (0.901- 1.933) | 0.154 | |
| Lymph node metastases (yes vs. no) | 2.579 | (1.790- 3.715) | <0.001 | 2.369 | (1.515 -3.705) | <0.001 | |
| LMR (>3.8 vs. ≤3.8 ) |
0.402 | (0.272- 0.594) | <0.001 | 0.459 | (0.306- 0.688) | <0.001 | |
| CA125(U/ml) (≤34 vs.>34) |
1.802 | (1.181- 2.749) | 0.006 | 1.946 | (1.256- 3.015) | 0.003 | |
The multivariate Cox regression model demonstrated that LMR≤3.8 (HR = 0.459, 95% CI: 0.306-0.688, P = <0.001), and CA125>34 U/ml (HR = 1.946, 95% CI: 1.256-3.015, P = 0.003) were significantly associated with OS. BMI, body mass index; FIGO, Federation of Gynecologists and Obstetricians; LMR, lymphocyte/monocyte ratio; CA125: cancer antigen 125.