Table 3. Dissolving Thermodynamic Data of Azilsartan in Different Solvents.
solvent | ΔsolH° (kJ·mol–1) | ΔsolS° (J·K–1·mol–1) | ΔsolG° (kJ·mol–1) | % ζH | % ζTS |
---|---|---|---|---|---|
methanol | 12.5957 | 35.297 | 1.565 | 53.312 | 46.688 |
ethanol | 12.9615 | 36.254 | 1.632 | 53.359 | 46.641 |
acetonitrile | 26.3828 | 64.913 | 6.097 | 56.532 | 43.468 |
n-propanol | 26.4377 | 72.866 | 3.666 | 53.725 | 46.275 |
isopropanol | 27.4736 | 74.287 | 4.258 | 54.200 | 45.800 |
tetrahydrofuran | 8.6881 | 23.489 | 1.348 | 54.204 | 45.796 |
methanol/water (8/2, v/v) | 20.913 | 55.701 | 3.506 | 54.574 | 45.426 |
ethanol/water (8/2, v/v) | 16.194 | 45.329 | 2.028 | 53.340 | 46.660 |
ethanol/water (5/5, v/v) | 34.8772 | 90.548 | 6.580 | 55.208 | 44.792 |