Table 2.

Effect of intensive blood pressure control on cardiac structure and function

		Baseline	Follow-up	Delta^*	Follow-up
Measure	Group	Mean±SD	Mean±SD	Mean±SD	LS Mean (95% CI) ^†	p-value
LV Mass (g)	INT	98.0±22.6	94.4±21.74	−2.7±6.4	96.8(95.6, 97.9)	0.37
	STD	103.1±26.8	99.9±25.34	−2.3±8.4	97.5(96.4, 98.7)	0.37

LV End Diastolic Volume (ml)	INT	124.7±26.9	125.3±26.4	2.4±11.5	127.6(125.7, 129.4)	0.01
	STD	128.8±30.0	126.7±28.4	−1.6±12.8	124.3(122.4, 126.2)	0.01

LV Mass/LV End Diastolic Volume	INT	0.8±0.1	0.8±0.13	−0.04±0.09	0.76(0.75, 0.78)	0.002
	STD	0.8±0.2	0.8±0.16	−0.01±0.09	0.79(0.78, 0.81)	0.002

LV End Systolic Volume (ml)	INT	48.6±15.3	49.4±14.64	1.3±6.9	50.5(49.4, 51.5)	0.18
	STD	50.7±16.6	50.5±15.88	0.0±7.0	49.5(48.4, 50.5)	0.18

Stroke Volume (ml)	INT	76.3±15.1	75.8±14.69	0.9±7.8	77.1(75.9, 78.3)	0.02
	STD	78.2±16.8	76.4±15.96	−1.7±8.4	75.0(73.8, 76.3)	0.02

Cardiac Output (ml/min)	INT	4863±1301	4778±1170	26.5±796.5	4779(4663, 4895)	0.15
	STD	4797±1068	4905±1129	154.1±715.2	4900(4781, 5020)	0.15

LV Ejection Fraction (%)	INT	61.7±6.1	61.0±5.23	−0.6±3.3	60.8(60.4, 61.3)	0.89
	STD	61.2±6.0	60.7±5.84	−0.6±3.3	60.8(60.3, 61.3)	0.89

Myocardial native T1 values (msc)	INT	947.4±25.9	956.2±25.3	10.0±26.2	958.6(954.2, 962.9)	0.79
	STD	952.8±29.3	960.1±30.0	7.2±26.5	959.5(955.0, 963.9)	0.79

SD indicates standard deviation; LS, Least Squares; CI, Confidence Interval; EDV, end diastolic volume; ESV, end systolic volume; LV, left ventricular; msc, milliseconds; INT, Intensive Treatment; STD, Standard treatment.

Difference of follow-up measure minus baseline.

^†

Adjusted for baseline value, age, sex, and body surface area.