Table 4.
Association between 18-month change in cardiac MRI measures and incidence of the primary composite cardiovascular outcome following the 18-month study visit
HR (95% CI) | p-value | |
---|---|---|
Measure | per 1 SD decrease | |
Change in LV Mass (g) | 1.39(0.95, 2.03) | 0.094 |
Change in LV End Diastolic Volume (ml) | 0.84(0.52, 1.37) | 0.486 |
Change in LV Mass/LV End Diastolic Volume | 1.15(0.71, 1.87) | 0.561 |
Change in LV End Systolic Volume (ml) | 0.91(0.57, 1.47) | 0.707 |
Change in Stroke Volume (ml) | 0.81(0.50, 1.31) | 0.391 |
Change in Cardiac Output (ml/min) | 0.72(0.45, 1.16) | 0.652 |
Change in LV Ejection Fraction (%) | 0.82(0.50, 1.36) | 0.450 |
Change in Myocardial native T1 (milliseconds) | 0.88(0.51, 1.52) | 0.652 |
HR indicates Hazard Ratio based on Cox proportional hazards regression adjusting for baseline value; LV, Left Ventricular; SD, Standard Deviation. Primary cardiovascular composite endpoint includes myocardial infarction, acute coronary syndrome, stroke, heart failure, or death from cardiovascular causes.