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. 2020 Mar 26;11:136. doi: 10.1186/s13287-020-01637-3

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — CS-IGF-1C hydrogel increased hP-MSC survival in vivo. a Representative BLI of mice transplanted with hP-MSCs, hP-MSCs + CS hydrogel, or hP-MSCs + CS-IGF-1C hydrogel. b Quantitative analysis of BLI signals showed that cell survival was improved by CS-IGF-1C hydrogel. Data are expressed as mean ± SEM. *P < 0.05 versus hP-MSCs; ^#P < 0.05 versus hP-MSCs + CS. c Representative photomicrographs displayed the engraftment of GFP⁺ hP-MSCs delivered with CS-IGF-1C hydrogel, CS hydrogel, or PBS on day 7. Scale bar, 100 μm. d Quantification analysis of GFP⁺ hP-MSCs delivered with CS-IGF-1C hydrogel, CS hydrogel, or PBS. **P < 0.01 versus PMSCs