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. 2011 Jun 15;2011(6):CD002800. doi: 10.1002/14651858.CD002800.pub3

Pierrugues 1989.

Methods Randomised clinical trial.
Participants Twenty‐nine patients were included in the study (17 males and 12 females, mean age 45.8 years ± 11) with alcoholic hepatitis, 14 in the PTU group and 15 in the placebo group.
Diagnostic assessment: alcoholic hepatitis with liver biopsy.
Interventions Experimental group: 
 PTU 300 mg/day orally.
Control group: 
 placebo.
Duration of treatment: 28 days.
Outcomes All‐cause mortality. 
 Biochemistry. 
 Liver histology. 
 Thyroid function.
Notes Sent letter in 2001. No reply.
Only published as abstract.
A composite clinical and laboratory index was used to evaluate the effect of PTU, but details on which index that was used are not given.
Risk of bias
Bias Authors' judgement Support for judgement
Selective reporting (reporting bias) Low risk All the important outcomes were reported.
Free of academic bias Low risk Comment: No previous trial of the same comparison by the same authors was identified.