Serrano‐Cancino 1981.

Methods	Randomised clinical trial.
Participants	Forty‐one patients were studied with severe alcoholic hepatitis (21 in the PTU and 20 in the placebo group). At entry there were no significant difference in the clinical severity (ascites, encephalopathy, s‐bilirubin, s‐albumin, s‐creatinin, white blood cell count) between the placebo and the PTU group.
Interventions	Experimental group: PTU 100 mg every eight hours orally. Control group: placebo. Duration of treatment: 17.0 ± 13.3 days. Additional treatment in both groups: standard nutritional and supportive diet.
Outcomes	All‐cause mortality. Biochemistry. Adverse events. Duration of hospital stay.
Notes	Sent letter in 2001. No reply. Only published as abstract.
Risk of bias
Bias	Authors' judgement	Support for judgement
Selective reporting (reporting bias)	Low risk	All the important outcomes were reported.
Free of academic bias	Low risk	Comment: No previous trial of the same comparison by the same authors was identified.

PTU = propylthiouracil. 
 y = year(s). 
 h = hour(s). 
 > = more than, greater than. 
 < = less than.