Table 3.
Comparison of clinical factors among the earlier group and appropriate group in relation to those who underwent emergency surgery
| Earlier (n = 23) | Appropriate (n = 13) | p value | |
|---|---|---|---|
| Surgical indication, n | |||
| Perforation/hemorrhage/toxic megacolon/ | |||
| severity/fulminant course | 1/3/4/15/0 | 0/3/1/9/0 | 0.648 |
| Postoperative follow-up observation, months | 64 (20–348) | 132 (64–307) | 0.002 |
| Period from onset until IPAA, months | 26 (1–192) | 25 (1–122) | 0.818 |
| Total steroid dose, mg | 2,640 (180–56,684) | 4,360 (1,540–12,700) | 0.401 |
| Preoperative steroid dose/day, mg | 60 (0–120) | 60 (20–80) | 0.624 |
| Preoperative WBC, /µL | 8,395 (3,270–16,960) | 9,650 (4,570–16,270) | 0.473 |
| Preoperative CRP, mg/dL | 1.4 (0.15–15.9) | 1.8 (1.0–11.0) | 0.781 |
| Preoperative Alb, g/dL | 2.8 (2.0–4.3) | 2.7 (2.0–4.0) | 0.626 |
| Thiopurine use, n (%) | 5 (21.7) | 0 (0) | 0.089 |
| Calcineurin inhibitor use, n (%) | 2 (8.7) | 0 (0) | 0.402 |
| Use of leukocytapheresis, n (%) | 14 (60.9) | 6 (46.2) | 0.493 |
Values are medians (ranges) unless otherwise indicated. Alb, albumin; CRP, C-reactive protein; IPAA, ileal pouch anal anastomosis; WBC, white blood cell count.