Figure 5.

Effects of the dilution factors on the bioavailability of various polycyclic hydrocarbon molecular classes in DMSO extracts of petroleum substances. A and B, are bioavailable fractions at different dilutions as compared with the neat DMSO extract of each petroleum substance. Gray bars represent the bioavailable fractions of aromatic compounds in cell medium (cardiomyocyte), which were derived from the protein binding analysis via SPME at 2 dilutions, 0.5% (A) and 0.005% (B) of the beginning DMSO extract. (C) and (D) are chemical profiles of the polycyclic hydrocarbon molecular classes in the cell culture media at different dilution. (C) is for 0.5% and (D) is for 0.005% final concentration of the neat DMSO extract.