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. 2020 Feb 10;174(2):218–240. doi: 10.1093/toxsci/kfaa015

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Figure 4. — Representative concentration-dependent effects on arachidonic acid metabolism in human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) following cardiotoxicant exposure. Arachidonic acid (■) and cell viability (●) concentration-response curves are shown for (A) rosiglitazone, (B) ondansetron, (C) verapamil, (D) amiodarone, (E) arsenic trioxide, and (F) cisapride. The x-axis is the drug concentration (µM) and the y-axis is the solvent control-normalized (fold change) value for arachidonic acid or cell viability. Data represent mean ± SEM (n = 3). If not shown, error bars are smaller than the size of the symbol.