1.11. Analysis.

Comparison 1 DRUG VERSUS PLACEBO, Outcome 11 Manometry.

Manometry
Study	Domain	Drug (n = 17); reported as mean (SD)	Placebo (n = 12); reported as mean (SD)
Phenylephrine gel versus placebo
Park 2007	Resting pressure (mmHg)	Baseline: 30.0 (12.3); After: 27.3 (12.7) P = 0.362	Baseline: 32.6 (14.2); After: 27.2 (15.0) P = 0.306
Park 2007	Squeezing pressure (mmHg)	Baseline: 143.3 (60.5); After: 160.4 (76.9) P = 0.083	Baseline: 152.6 (86.5); After: 147.1 (76.5) P = 0.625
Park 2007	Sustained duration (s)	Baseline: 41.9 (24.5); After: 44.9 (48.3) P = 0.848	Baseline: 39.6 (24.4); After: 32.8 (14.4) P = 0.187
Park 2007	Sphincter length (cm)	Baseline: 3.2 (0.9); After: 3.4 (0.8) P = 0.368	Baseline: 3.5 (0.8); After: 3.4 (0.8) P = 0.743
Park 2007	High pressure zone (cm)	Baseline: 2.4 (2.1); After: 1.9 (0.5) P = 0.378	Baseline: 2.1 (0.9); After: 2.3 (0.9) P = 0.556