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. 2013 Jun 11;2013(6):CD002116. doi: 10.1002/14651858.CD002116.pub2

1.14. Analysis.

Comparison 1 DRUG VERSUS PLACEBO, Outcome 14 Sensory threshold (cm water).

Sensory threshold (cm water)
Study Drug Placebo
Loperamide versus placebo
Hallgren 1994 # N 28 mean 29.6 (SD 11.7) N 28 mean 26.5 (SD 14.9)
Diphenoxylate + atropine versus placebo
Harford 1980 # N 15 mean 12 (SD 12) N 15 mean 31 (SD 62)