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. 2013 Jun 11;2013(6):CD002116. doi: 10.1002/14651858.CD002116.pub2

1.15. Analysis.

Comparison 1 DRUG VERSUS PLACEBO, Outcome 15 Saline retention test (mL).

Saline retention test (mL)
Study Drug Placebo Significance
Loperamide versus placebo
Sun 1997 # N 11 mean 223 (SD 274)
 (loperamide oxide) versus
 N 11 mean 150 (SD 208 ) P = 0.07
Diphenoxylate + atropine versus placebo
Harford 1980 # N 15 mean 492 (SD 461) N 15 mean 486 (SD 364)