| Number of people failing to achieve full continence | |||
|---|---|---|---|
| Study | Drug | Placebo | Significance |
| Loperamide versus placebo | |||
| Hallgren 1994 # | 3/28 during the day 1/28 during the night | 7/28 during the day 11/28 during the night | |
| Sun 1997 # | 4/11 in 24 hours (loperamide oxide) | 8/11 in 24 hours | P < 0.05 |
| Diphenoxylate + atropine versus placebo | |||
| Harford 1980 # | 0/15 in 24 hours | 3/15 in 24 hours | |
| Phenylephrine gel versus placebo | |||
| Carapeti 2000b # | 8/12 | 12/12 | |
| Sodium valproate versus placebo | |||
| Kusunoki 1990 # | 3/17 | 10/17 | |
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