Figure 4. Comparison of reported error rates from error-correction techniques.

The error rates are included along with the indicated oligo source and error-correction methodology. When starting error rates were unreported, we estimated the error rates on the basis of the oligo sources and assembly method. Open circles denote starting error rates; filled circles denote error rates of assembled genes (two filled circles denote error rates before and after error correction). ssDNA, single-stranded DNA; dsDNA, double-stranded DNA; Column, column-synthesized oligos; Array, microarray-based oligo pools; Hyb, oligo hybridization–based error correction; Seq, NGS-based error correction; Lig, high-temperature ligation/hybridization–based error correction; Nuclease, nuclease-based error correction.