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. 2009 Oct 7;2009(4):CD002192. doi: 10.1002/14651858.CD002192.pub2

Clark 1981.

Methods Anaesthetic drugs used: thiopentone, fentanyl 1.5 microg/kg and 70% N2O in O2 with thiopentone increments or thiopentone, 70% N2O in O2 and enflurane 2‐4% 
 Premed‐induction interval: 30‐60 
 (minutes)
Participants 100
Interventions Drug(s) and dose: pethidine 1mg/kg plus atropine 0.01mg/kg vs. placebo 
 (intramuscular)
Outcomes Times from emergence to walking, retaining oral fluids, voiding
Notes 1) No assessment of preoperative anxiety ‐ not focus of study 
 2) Difference from placebo? No
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk Method of randomization unknown
Allocation concealment? Unclear risk Unclear