| Methods |
Anaesthetic drugs used: propofol, sufentanil 0.2mcg.kg, mivacurium, O2, 66% N2O, desflurane >1.2 MAC.
Premed‐Induction interval 60‐90 mins |
| Participants |
45 |
| Interventions |
Drug(s) and dose: alprazolam 0.5mg vs. midazolam 7.5mg vs. placebo |
| Outcomes |
Discharge time from PACU, Discharge time from clinic, DSST and TDT |
| Notes |
1) Patient assessed preop anxiety reduced with both midazolam and alprazolam. Sedation was greater with alprazolam
2) Difference from placebo? No difference in discharge time from PACU. TDT and DSST affected by midazolam and alprazolam at time of discharge from PACU but returned to baseline by time of discharge from clinic |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Adequate sequence generation? |
Unclear risk |
Method of randomization unknown |
| Allocation concealment? |
Unclear risk |
B ‐ Unclear |
