Dyck 1991.

Methods	Anaesthetic drugs used: thiopentone 5mg/kg plus 1mg/kg. Fentanyl 0.5microg/kg. 60% N2O in O2 with enflurane Premed‐induction interval: 60‐90 (minutes)
Participants	92
Interventions	Drug(s) and dose: propranolol 80mg vs. diazepam 10mg vs. placebo
Outcomes	Digit span, TDT hourly for three hours from emergence
Notes	1) Anxiety assessed by State‐Trait Anxiety Inventory. No evidence of a difference from placebo ‐ all patients became less anxious 2) Difference from placebo? Diazepam impaired performance at 1 and 2 but not at 3 hours
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	Low risk	Randomization using random number tables
Allocation concealment?	Low risk	Adequate