| Methods |
Anaesthetic drugs used: methohexitone, fentanyl 1microg/kg, 70% N2O in O2; halothane 0.5% increments as required
Premed‐induction interval: 90
(minutes) |
| Participants |
120 |
| Interventions |
Drug(s) and dose: midazolam 15mg vs. triazolam 0.25mg vs. diazepam 10mg vs. placebo |
| Outcomes |
Memory and letter deletion tests at 30 mins, 2 and 4 hours. Readiness for discharge and Romberg's test 4 hours post‐operatively |
| Notes |
1) Patients' own assessment of preoperative effect by visual analogue scale for anxiety and sedation ‐ significant reduction after active treatment for sedation only
2) Difference from placebo? Letter deletion test impaired by midazolam and triazolam at 4 hours but no difference in readiness for discharge |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Adequate sequence generation? |
Low risk |
Method of randomization unknown |
| Allocation concealment? |
Low risk |
Coded sealed envelopes used |
