| Methods |
Anaesthetic drugs used: methohexitone, 70% N2O in O2, methohexitone infusion with boluses as required
Premed‐induction interval: 30‐60
(minutes) |
| Participants |
150 |
| Interventions |
Drug(s) and dose: midazolam 5mg vs. placebo (intramuscular) then fentanyl 100microg vs. oxymorphone 1mg vs. placebo (intravenous) |
| Outcomes |
Times from end of anaesthesia to ambulation and discharge |
| Notes |
1) Patients asked to characterise effect of second injection as pleasant, unpleasant or no change. Visual analogue score used for anxiety and sedation ‐ both significantly affected by midazolam
2) Difference from placebo? No |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Adequate sequence generation? |
Low risk |
Computer generated random number list |
| Allocation concealment? |
Low risk |
Allocation concealment by independent pharmacist |
