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. 2009 Oct 7;2009(4):CD002192. doi: 10.1002/14651858.CD002192.pub2

Turner 1991.

Methods Anaesthetic drugs used: propofol, N2O, O2 and isoflurane. Fentanyl 1microg/kg 
 Premed‐induction interval: 60 
 (minutes)
Participants 74
Interventions Drug(s) and dose: midazolam 10mg vs. temazepam 20mg vs. placebo
Outcomes Memory, letter deletion 3 hours postoperatively
Notes 1) Patients' linear analogue scale showed both midazolam and temazepam better than placebo preoperatively 
 2) Difference from placebo? Not for memory. Temazepam group showed better performance on letter deletion than placebo 
 ‐ authors suggest Type I error
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk Method of randomization unknown
Allocation concealment? Unclear risk Not clear

DSST: Digital Symbol Substitution Test; Mins: Minutes; PACU: Post Anaesthesia Care Unit; STAI: State‐Trait Anxiety Inventory; TDT: Treiger Dot Test ; VAS: Visual Analogue Scale