Turner 1991.
| Methods | Anaesthetic drugs used: propofol, N2O, O2 and isoflurane. Fentanyl 1microg/kg Premed‐induction interval: 60 (minutes) | |
| Participants | 74 | |
| Interventions | Drug(s) and dose: midazolam 10mg vs. temazepam 20mg vs. placebo | |
| Outcomes | Memory, letter deletion 3 hours postoperatively | |
| Notes | 1) Patients' linear analogue scale showed both midazolam and temazepam better than placebo preoperatively 2) Difference from placebo? Not for memory. Temazepam group showed better performance on letter deletion than placebo ‐ authors suggest Type I error | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Adequate sequence generation? | Unclear risk | Method of randomization unknown |
| Allocation concealment? | Unclear risk | Not clear |
DSST: Digital Symbol Substitution Test; Mins: Minutes; PACU: Post Anaesthesia Care Unit; STAI: State‐Trait Anxiety Inventory; TDT: Treiger Dot Test ; VAS: Visual Analogue Scale