#1	explode "premedication‐" / all SUBHEADINGS in DEM,DER,DRM,DRR
#2	ambulatory an?est*
#3	prean?est* or pre?medic*
#4	explode "anxiolytic‐agent" / all SUBHEADINGS in DEM,DER,DRM,DRR
#5	anxioly*
#6	prean?est* medication
#7	#1 or #2 or #3 or #4 or #5 or #6
#8	"surgery‐" / all SUBHEADINGS in DEM,DER,DRM,DRR
#9	explode "ambulatory‐surgery" / all SUBHEADINGS in DEM,DER,DRM,DRR
#10	surgical (procedur* or operat*)
#11	day case or out?patient* or ambulat*
#12	#8 or #9 or #10 or #11
#13	#7 and #12
#14	explode "randomized‐controlled‐trial" / all SUBHEADINGS in DEM,DER,DRM,DRR
#15	(randomi?ed controlled trial*) in TI, AB
#16	random*
#17	explode "randomization‐" / all SUBHEADINGS in DEM,DER,DRM,DRR
#18	randomi?ation
#19	explode "clinical‐trial" / all SUBHEADINGS in DEM,DER,DRM,DRR
#20	clinical near trial*
#21	explode multicenter‐study / all subheadings
#22	multi?cent*
#23	explode phase‐4‐clinical‐trial / all subheadings or explode double‐blind‐procedure / all subheadings or explode single‐blind‐procedure / all subheadings
#24	(RANDOM* or CROSS?OVER* or FACTORIAL* or PLACEBO* or VOLUNTEER*) in TI, AB, TW
#25	((SINGL* or DOUBL* or TREBL* or TRIPL*) near (BLIND* or MASK*)) in TI,AB
#26	#14 or #15 or #16 or #17 or #18 or #19 or #20 or #21 or #22 or #23 or #24 or #25
#27	(human) in DER
#28	(animal or nonhuman) in DER
#29	#27 and #28
#30	#28 not #29
#31	#26 not #30
#32	#13 and #31