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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Lancet Diabetes Endocrinol. 2020 Jan 29;8(3):249–256. doi: 10.1016/S2213-8587(20)30022-X

Figure 2. Hypothetical secretory reserve concept.

Figure 2.

This figure depicts the activity of a hypothetical insulin secretory reserve compartment with changes that may occur with differences in insulin sensitivity or with a fall in β-cell mass with T1D. The β-cell mass of the Y-axis could represent either actual mass or effective mass, or a mixture thereof.