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. 2020 Mar 26;15(3):e0229903. doi: 10.1371/journal.pone.0229903

Table 2. Univariate logistic regression analysis on pCR (Y [pCR] vs N [no pCR]).

Variables Levels Odds Ratio (95% CI) P-value
Age (N = 45) 0.967 (0.91–1.023) 0.2555
Menopausal status (N = 44) Post vs Peri 0.412 (0–7.824) 0.5833
Pre vs Peri 0.5 (0–9.5) 0.6667
ER expression (%) (N = 45) 0.949 (0.896–1.005) 0.0727
ER positivity (N = 45) Pos vs Neg 0.077 (0.002–0.637) 0.0091
PR expression (%) (N = 45) 0.788 (0.554–1.122) 0.1868
PR positivity (N = 45) Pos vs Neg 0.087 (0–0.462) 0.0095
HER2 (N = 45) Pos vs Neg 1.365 (0.277–6.291) 0.8945
Ki67 (N = 45) 1.014 (0.977–1.052) 0.4761
Clinical T classification (N = 45) T3 or T4 vs T1 or T2 1.174 (0.250, 6.439) 1.000
Clinical N classification (N = 45) N1 vs N0 0.739 (0.067–11.208) 1.0000
N2 vs N0 1.299 (0.059–29.113) 1.0000
N3 vs N0 0.724 (0.072–10.364) 1.0000
Grade (N = 42) >2 vs ≤2 7.056 (0.820, 341.457) 0.0907
Surgery (N = 45) BCS vs Mastectomy 0.457 (0.009–4.767) 0.8653
Epithelial CTCs at T0 (N = 43) 0.989 (0.964–1.016) 0.4350
EMT-CTCs at T0 (N = 43) 0.977 (0.936–1.020) 0.2874

ER, estrogen receptor; PR, progesterone receptor; BCS, breast conserving surgery; CTC, circulating tumor cell; EMT, epithelial-mesenchymal transition