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. 2020 Mar 26;15(3):e0228740. doi: 10.1371/journal.pone.0228740

Table 1. Evaluation of the anti-amastigote activity in Leishmania amazonensis and cytotoxicity with mouse peritoneal macrophages Swiss.

Compounds IC50-AMA (μmoL L-1)* CC50 (Peritoneal Macrophages) (μmoL L-1)* IS
RP1 1.25±0.70 >100±0.02 80
Fc-RP1 0.25±0.38 17.3±0.03 69
Ferrocene carboxylic acid 4.4±0.91 >100 ±0.03 22
Amphotericin B 0.63±1.17 17.73±0.05 28

*Results are expressed by the mean of the duplicates plus the standard deviation.