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. Author manuscript; available in PMC: 2020 May 18.
Published in final edited form as: Nat Chem. 2019 Nov 18;11(12):1106–1112. doi: 10.1038/s41557-019-0358-y

Table 3.

Reaction scope

graphic file with name nihms-1540634-t0008.jpg

*Reaction conditions: 5 (0.30 mmol), 2 (0.90 mmol), 3 (0.45 mmol), Pd(cod)Cl2 (0.03 mmol), L1 (0.03 mmol), N11 (0.15 mmol), 5-trifluomethyl-2-pyridinol (0.06 mmol), Cs2CO3 (0.90 mmol), 1,4-dioxane (6 mL), 100 °C, 16 h.

a

The corresponding alkenyl bromides were used instead of 5.

b

The corresponding alkenyl iodide was used instead of 5.

c

L2 (0.03 mmol) was used instead of L1.

d

N11 (0.30 mmol) was used, K3PO4 (0.90 mmol) was used instead of Cs2CO3, and a mixed solvent of 1,4-dioxane (3 mL) and toluene (3 mL) was used instead of 1,4-dioxane alone.