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. 2020 Jan 30;5(2):e132114. doi: 10.1172/jci.insight.132114

Figure 2. Implant-evoked photoreceptor degeneration induces local hyperactivity of RGCs.

Figure 2

(A) Multi-electrode array (MEA) recordings before (left) and after (right) adding neurotransmitter receptor blockers, in degenerated (red) and control (black) samples taken from implanted retinas. (B) Quantification of spontaneous dark activity for degenerated (n = 5) and control (n = 5) retinal samples. Values represent mean firing rate ± SEM. *P < 0.05; **P < 0.01; 2-tailed t test.