TABLE 1.
Genotypic characterization of BDQ mutant isolates used in the EQA panel
Site | Isolate IDa | Gene target(s) | Nucleotide mutation | Amino acid mutation |
---|---|---|---|---|
Institute of Tropical Medicine (Antwerp, Belgium) | 1 | atpE | G187C | Ala63Pro |
2 | Rv0678 | T276A | Tyr92STOP | |
3 | Rv0678 | C403T | Ala131Trp | |
South African National Institute for Communicable Diseases | 1 | Rv0678/atpE | 201_206delCAGCAC/A83C | Ser68_Thr69del/Asp28Ala |
2 | Rv0678 | T131C | Leu44Pro |
ID, identifier.