TABLE 5.
Interlaboratory reproducibility of DST methodsa
| DST methods | CC/BP | N | All (%) | Wild type (%) | Rv0678 (%) | atpE (%) |
|---|---|---|---|---|---|---|
| Agar proportion | 0.25 | 577 | 96.0 | 98.6 | 85.0 | 100.0 |
| BMD frozen | 0.12 | 572 | 97.0 | 96.8 | 97.2 | 100.0 |
| BMD dry | 0.12 | 584 | 99.5 | 99.3 | 100.0 | 100.0 |
| MGIT960 | 1 | 594 | 99.8 | 99.8 | 100.0 | 100.0 |
a
Critical concentration data (indicated in micrograms per milliliter) apply to the agar proportion and MGIT960 methods, and MIC breakpoint data (indicated in micrograms per milliliter) apply to both frozen and dry microtiter plates using the BMD method. BMD, broth microdilution; BP, breakpoint; CC, critical concentration; DST, drug susceptibility testing; MGIT, Mycobacteria Growth Indicator Tube.