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. 2020 Mar 25;58(4):e01677-19. doi: 10.1128/JCM.01677-19

TABLE 6.

BDQ DST methods and interpretive criteriaa

DST method CC/BP
(μg/ml)
Value for indicated interpretive criterion
Susceptible Resistant
MGIT 1b GU ≤ 100 GU > 100
7H9 broth MIC (BMD) 0.12c ≤0.12 μg/ml ≥0.25 μg/ml
Agar proportion 0.25d <1% ≥1%
a

BDQ, bedaquiline; BP, breakpoint; CC, critical concentration; DST, drug susceptibility testing; GU, growth unit.

b

Critical concentration.

c

MIC breakpoint; applies to both frozen and dry microtiter plates.

d

Critical concentration; applies to both 7H10 agar and 7H11 agar.