TABLE 2.
Beta-d-glucan diagnostic performance on cerebrospinal fluid in fungal meningitis by cohort
| Organism(s) | % (no./total no.) for: |
CSF BDG concn cutoff used (pg/ml)a | |
|---|---|---|---|
| Sensitivity | Specificity | ||
| Exserohilum rostratum (23) | 100 (41/41) | 98 (65/66) | 138 |
| 99 (40/41) | 98 (65/66) | 230 | |
| Exserohilum rostratum, Aspergillus species (30)b | 96 (27/28) | 95 (128/135) | 80 |
| Histoplasma capsulatum (26) | 53 (25/47) | 87 (133/153) | 80 |
| Cryptococcus neoformans (27) | 89 (69/78) | 85 (33/39) | 80 |
| Coccidioides species (28) | 96 (25/26) | 82 (9/11) | 31 |
a
The clinically recommended cutoff value is 80 pg/ml.
b
Multiple organisms included in the cohort.