Table 2.
Summary of the resolution of different imaging techniques
| Technique | Lateral resolution | Axial resolution | Reference |
|---|---|---|---|
| Confocal | 200 nm | 500–700 nm | Schulz et al. (2013), MacDonald et al. (2015) |
| TIRFM | 200 nm | Up to 100 nm | Axelrod (2001), Mattheyses et al. (2010) |
| SIM | 100 nm | 250 nm | Gustafsson (2000) |
| PALM | Up to 20 nm | 50 nm | Betzig et al. (2006) |
| STORM | Up to 20 nm | 50 nm | Rust et al. (2006) |
Abbreviations: PALM, photoactivation localization microscopy; SIM, structured illumination microscopy; STORM, stochastic optical reconstruction microscopy; TIRFM: total internal reflection fluorescence microscopy.