Table 1:
Patient Characteristics of Neonatal Intubations, by Setting
| NICU n=2279 |
Delivery Room n=866 |
p-value | |
|---|---|---|---|
| Weight at intubation, grams; median (IQR) | 1650 (950, 2947) | 1244 (770, 2700) | <0.001 |
| GA at birth, weeks; median (IQR) | 28 (25, 34) | 29 (26, 36) | <0.001 |
| Postnatal age, days; median (IQR) | 10 (1, 47) | N/A | N/A |
| Diagnosis:* n (%) | |||
| Acute Respiratory Failure | 1415 (62.1%) | 647 (74.7%) | <0.001 |
| Congenital Anomaly Requiring Surgery | 146 (6.4%) | 149 (17.2%) | <0.001 |
| Congenital Heart Disease | 136 (6.0%) | 83 (9.6%) | <0.001 |
| Neurologic Impairment | 149 (6.5%) | 21 (2.4%) | <0.001 |
| Sepsis | 144 (6.3%) | 14 (1.6%) | <0.001 |
| Airway and/or Craniofacial Anomaly | 114 (5.0%) | 21 (2.4%) | 0.001 |
| Chronic Respiratory Failure | 516 (22.6%) | 2 (0.2%) | <0.001 |
| Indication;* n (%) | |||
| Ventilation Failure | 811 (35.6%) | 109 (12.6%) | <0.001 |
| Oxygen Failure | 692 (30.4%) | 180 (20.8%) | <0.001 |
| Surfactant administration | 508 (22.3%) | 291 (33.6%) | <0.001 |
| Frequent Apnea and Bradycardia Events | 450 (19.7%) | 41 (4.7%) | <0.001 |
| Reintubation after Unplanned Extubation | 283 (12.4%) | 5 (0.6%) | <0.001 |
| Procedure | 232 (10.2%) | 2 (0.2%) | <0.001 |
| Other | 106 (4.7%) | 6 (0.7%) | <0.001 |
| Upper Airway Obstruction | 92 (4.0%) | 4 (0.5%) | <0.001 |
| Unstable Hemodynamics | 49 (2.2%) | 21 (2.4%) | 0.64 |
| DR, Clinical Indication | N/A | 601 (69.4%) | N/A |
| DR, Routine Practice for Diagnosis** | N/A | 123 (14.2%) | N/A |
NICU= neonatal intensive care unit, DR= delivery room, GA= gestation age, IQR= interquartile range, N/A= not applicable
*
More than one indication can be selected for a given encounter. Diagnosis and indications occurring in <1% of the population not reported
**
DR- Routine Practice for Diagnosis= TI based on a specific diagnosis, i.e. certain hospitals may intubate all neonates below a certain GA or all neonates with a certain diagnosis such as congenital diaphragmatic hernia