Figure 2.

Treatments with EGF and/or hGly²GLP-2 increase colonic weight in C57Bl/6 mice. Male (n = 4–5) and female (n = 4–5) 6- to 8-week C57Bl/6 mice were treated for 11 days with various combinations of vehicle, EGF, and/or hGly²GLP-2. (A) Colonic weight, (B) Colonic length, (C) Colonic weight/body weight and (D) Colonic weight/small intestinal length. All data were normalized by sex prior to combination within each treatment group to make n = 8–9. *P < 0.05, **P < 0.01, ***P < 0.001 as indicated; ###P < 0.001 vs hGly²GLP-2 alone.