Table 2.
Baseline characteristics.
| Patient characteristic | Cohort I (n = 83) | Cohort II (n = 35) | p value |
|---|---|---|---|
| Male, n (%) | 50 (60.2) | 19 (54.3) | 0.55 |
| Gestational age, median weeks+days (range) | 40+1 (36+0–42+4) | 39+6 (36+3–41+6) | 0.18 |
| Birth weight, median in gram (range) | 3500 (2260–5000) | 3425 (1780–4440) | 0.36 |
| Mode of delivery | 0.07 | ||
| Emergency caesarian section, n (%) | 46 (55.4) | 20 (57.1) | |
| Vaginal delivery, n (%) | 25 (30.1) | 6 (17.1) | |
| Vacuum extraction, n (%) | 12 (14.5) | 9 (25.7) | |
| Apgar score at 5 min, median (range) | 3 (0–10) | 3 (0–9) | <0.001 |
| First pH, median (range) | 6.96 (6.53–7.34) | 6.94 (6.60–7.28) | 0.67 |
| Thompson score, median (range) | 10 (4–19) | 11 (5–20) | 0.83 |
| Sarnat classification | 0.87 | ||
| Mild, n (%) | 5 (6.0) | 5 (14.3) | |
| Moderate, n (%) | 58 (69.9) | 19 (54.3) | |
| Severe, n (%) | 20 (24.1) | 10 (28.6) | |
| Incomplete hypothermia <72 h, n (%) | 6 (7.2) | 0 (0) | 0.10 |
| Postmenstrual age at CUS day 3–7, median days (range) | 4 (3–7) | 4 (3–7) | 0.49 |
| MRI available, n (%) | 77 (92.8) | N/A | N/A |
| Postmenstrual age at MRI, median days (range) | 6 (3–16) | N/A | N/A |
| Outcome | 0.26 | ||
| Normal, n (%) | 54 (65.1) | 17 (48.6) | |
| Adverse outcome <85, on BSITD-III, n (%) | 3 (3.6) | 7 (20.0) | |
| Death, n (%) | 26 (31.3) | 11 (31.4) |