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. 2020 Jan 31;39(13):2724–2740. doi: 10.1038/s41388-020-1178-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a C1GALT1 mRNA expression in normal and cancerous gastric tissues in the Oncomine database. b C1GALT1 expression in paired gastric tumors. Immunohistochemical staining revealed C1GALT1 expression in paired gastric adenocarcinoma tumor (right) and nontumor mucosa tissue (left). In nontumor mucosa, foveolar epithelial cells (upper left) expressed less C1GALT1 than glandular epithelial cells (lower left). The negative control (lower right) did not exhibit specific staining. Scale bar, 50 µm. C1GALT1 was frequently overexpressed in gastric adenocarcinoma tumor (T) compared with its surrounding nontumor mucosa (N). *p < 0.05, paired t test. c Scoring of C1GALT1 expression (0–1, 2, and 3) analyzed using immunohistochemistry. Scale bar, 50 µm. d Kaplan–Meier survival analysis according to the expression of C1GALT1 in gastric cancer patients (n = 98).