TABLE 2.
Differential OTUs selected by linear discriminant analysis effect size (LEfSe).
| OTUID | Phyla | Genus | Enriched group | LDA | p-value | HBV_mean | Healthy_mean |
| OTU637 | Bacteroidetes | Bacteroides | Healthy | 2.19 | 0.03 | 2.85E-04 | 1.12E-03 |
| OTU26 | Bacteroidetes | Parabacteroides | Healthy | 3.06 | 0.04 | 5.22E-2 | 5.33E-02 |
| OTU181 | Bacteroidetes | Prevotella | Healthy | 2.57 | 0.01 | 6.60E-03 | 1.31E-02 |
| OTU200 | Bacteroidetes | Prevotella | Healthy | 2.79 | 0.00 | 1.45E-03 | 1.88E-03 |
| OTU733 | Bacteroidetes | Prevotella | Healthy | 2.05 | 0.00 | 6.60E-05 | 2.46E-03 |
| OTU109 | Bacteroidetes | un_f_Barnesiellaceae | Healthy | 3.29 | 0.04 | 2.61E-02 | 4.52E-02 |
| OTU301 | Bacteroidetes | un_f_Barnesiellaceae | Healthy | 2.78 | 0.02 | 5.24E-03 | 1.20E-02 |
| OTU1038 | Bacteroidetes | un_f_S24-7 | Healthy | 2.17 | 0.00 | 6.60E-05 | 5.02E-04 |
| OTU255 | Bacteroidetes | un_f_S24-7 | Healthy | 2.80 | 0.05 | 1.19E-03 | 5.65E-03 |
| OTU286 | Bacteroidetes | un_f_S24-7 | HBV | 2.75 | 0.01 | 2.40E-03 | 2.51E-04 |
| OTU385 | Bacteroidetes | un_f_S24-7 | Healthy | 2.41 | 0.01 | 6.60E-05 | 5.01E-03 |
| OTU407 | Bacteroidetes | un_f_S24-7 | HBV | 2.33 | 0.03 | 1.42E-03 | 1.14E-03 |
| OTU764 | Bacteroidetes | un_f_S24-7 | Healthy | 2.02 | 0.03 | 1.32E-04 | 1.12E-03 |
| OTU83 | Firmicutes | Clostridium | HBV | 2.77 | 0.05 | 1.14E-02 | 8.86E-03 |
| OTU252 | Firmicutes | Lactobacillus | HBV | 2.35 | 0.05 | 3.18E-03 | 5.02E-04 |
| OTU254 | Firmicutes | Lactobacillus | HBV | 2.45 | 0.04 | 3.51E-03 | 0 |
| OTU282 | Firmicutes | Megasphaera | Healthy | 2.52 | 0.05 | 0 | 5.62E-03 |
| OTU380 | Firmicutes | Megasphaera | Healthy | 2.58 | 0.01 | 9.59E-04 | 5.83E-03 |
| OTU337 | Firmicutes | Phascolarctobacterium | HBV | 2.56 | 0.01 | 2.54E-03 | 1.05E-03 |
| OTU147 | Firmicutes | Ruminococcus | Healthy | 2.54 | 0.02 | 8.00E-03 | 1.42E-02 |
| OTU242 | Firmicutes | Ruminococcus | HBV | 2.52 | 0.03 | 1.56E-03 | 7.10E-04 |
| OTU244 | Firmicutes | Ruminococcus | Healthy | 2.25 | 0.01 | 4.02E-03 | 5.39E-03 |
| OTU638 | Firmicutes | Ruminococcus | Healthy | 2.03 | 0.03 | 2.53E-04 | 7.89E-04 |
| OTU523 | Firmicutes | un_f_Christensenellaceae | Healthy | 2.11 | 0.01 | 3.57E-04 | 1.68E-03 |
| OTU696 | Firmicutes | un_f_Mogibacteriaceae | HBV | 2.00 | 0.01 | 5.05E-04 | 0 |
| OTU1204 | Firmicutes | un_f_Ruminococcaceae | Healthy | 2.03 | 0.03 | 4.23E-04 | 8.57E-04 |
| OTU567 | Firmicutes | un_f_Ruminococcaceae | Healthy | 2.02 | 0.01 | 4.44E-04 | 1.92E-03 |
| OTU579 | Firmicutes | un_f_Ruminococcaceae | Healthy | 2.02 | 0.03 | 5.38E-04 | 1.21E-03 |
| OTU624 | Firmicutes | un_f_Ruminococcaceae | Healthy | 2.25 | 0.01 | 1.32E-04 | 3.55E-04 |
| OTU796 | Firmicutes | un_f_Ruminococcaceae | Healthy | 2.08 | 0.01 | 1.75E-04 | 2.51E-04 |
| OTU779 | Firmicutes | un_f_Veillonellaceae | Healthy | 2.08 | 0.01 | 1.14E-04 | 2.51E-04 |
| OTU801 | Firmicutes | un_o_Clostridiales | Healthy | 2.09 | 0.01 | 0 | 7.10E-04 |
| OTU847 | Firmicutes | un_o_Clostridiales | Healthy | 2.19 | 0.00 | 1.32E-04 | 2.51E-04 |
| OTU113 | Fusobacteria | Fusobacterium | HBV | 3.05 | 0.03 | 1.67E-02 | 1.94E-03 |
| OTU104 | Proteobacteria | Desulfovibrio | HBV | 3.18 | 0.01 | 1.29E-02 | 1.05E-02 |
| OTU263 | Proteobacteria | Sutterella | Healthy | 2.74 | 0.00 | 1.07E-03 | 6.51E-03 |
| OTU268 | Proteobacteria | Sutterella | HBV | 2.29 | 0.01 | 1.64E-03 | 1.29E-03 |
| OTU560 | TM7 | un_c_TM7-3 | Healthy | 2.05 | 0.00 | 3.57E-04 | 8.57E-04 |
p-values were adjusted with FDR method.