TABLE 2.

Mediation analysis models of the three-way association between left DG volume, Fornix FA, and percentage of correct rejections (n = 30).

Effect	Coefficient ± SE (% Mediation)	t	p	95% CI
Model A
Total effect c (fornix FA on % correct rejections)	3.13 ± 1.37	2.28	0.030*
a (fornix FA on left DG volume)	545.31 ± 189.80	2.87	0.008**
b (left DG volume on % correct rejections)	0.0028 ± 0.0013	2.10	0.045*
Mediation effect ab (fornix FA on % correct rejections via left DG volume)	1.50 ± 1.03 (48)	–	–	0.03, 4.57
Direct effect c′ (fornix FA on % correct rejections)	1.63 ± 1.47	1.10	0.279
Model B
Total effect c (left DG volume on % correct rejections)	0.0035 ± 0.0012	3.0	0.006**
a (left DG volume on fornix FA)	0.0004 ± 0.0001	2.87	0.008**
b (Fornix FA on % correct rejections)	1.63 ± 1.47	1.10	0.279
Mediation effect ab (left DG volume on % correct rejections via Fornix FA)	0.0007 ± 0.0006	–	–	−0.0005, 0.0019
Direct effect c′ (left DG volume on % correct rejections)	0.0028 ± 0.0013	2.10	0.045*

FA, fractional anisotropy; DG, dentate gyrus* indicates significance with p < 0.05 and ** indicates significance with p < 0.01. Significant bias-corrected CI are shown in bold.