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. 2020 Mar 26;11:1569. doi: 10.1038/s41467-020-15194-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Co-plot of the Δ normalized PRS and Δ normalized phenotypic value of 45 quantitative traits. The Δ normalized PRS (=normalized PRS in non-mainland−normalized PRS in mainland) is shown on the x-axis, and the Δ normalized phenotypic value (=normalized phenotypic value in non-mainland−normalized phenotypic value in mainland) is shown on the y-axis. Pearson’s correlation r and P value between the Δ normalized PRS and the Δ normalized phenotypic value are also described. The color of the dots represents the category of each trait. The right table shows the trait categories in color and the abbreviations of the traits. b Histograms of the PRS (top) and observed phenotypic value (bottom) for height (left) and BMI (right). In each panel, the distribution in the mainland is colored in gray, and that in non-mainland is colored in blue. The mean values of height and BMI retrieved from census data are shown in the middle, between the PRS and phenotypic histograms. The blue diamonds are the per-SD differences of height and BMI in non-mainland individuals. c Longitudinal census data of height (left) and BMI (right) in Japan. In each plot, the mean trait value of the general Japanese as a proxy of mainland (gray) and that of residents in Okinawa prefecture as a proxy of non-mainland (blue) are illustrated. The gray shadow indicates the 95% confidence interval.