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. 2020 Mar 26;10:5544. doi: 10.1038/s41598-020-62506-w

Figure 1.

Figure 1

Bofutsushosan (BFT) improved glucose metabolism without affecting body weight. (A) Body weight of mice treated with either saline (white) or BFT (black) on an high fat-diet (HFD) (n = 8–9). Average food (B) and water (C) intake of mice between 11 and 14 weeks of age (n = 8–9). Weight of epididymal adipose tissue (eWAT) (D) inguinal adipose tissue (iWAT) (E), brown adipose tissue (BAT) (F) and cecum (G) of mice treated with either saline or BFT (18–19 weeks of age, n = 8–11). (H) Oral glucose tolerance test (OGTT) and (I) AUC of HFD-fed mice treated with saline (white) or BFT (black) for 5 weeks (n = 18). (J) Plasma insulin levels in 2-hour-fasted state (n = 9–11, 18 weeks of age). (K) Insulin tolerance test (ITT) of HFD-fed mice treated with saline (white) or BFT (black) for 8 weeks (n = 18–19). *p < 0.05, **p < 0.01 by unpaired, 2-tailed t test.