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. 2020 Mar 26;10:5544. doi: 10.1038/s41598-020-62506-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Improvement of glucose metabolism with decreased adipose tissue inflammation by BFT– modified gut microbiota is transferable. (A) OGTT of HFD-fed mice treated with or without BFT before (left) (15 weeks old) and after (right) antibiotic treatment for 3 weeks. (B) OGTT of the HFD-fed recipient mice performed before (triangle) (17 weeks old) and after (circle) (26 weeks old) bacterial transfer from mice treated with saline (left) or BFT for 2 weeks (right) (n = 8). (C) ITT of the HFD-fed recipient mice performed before (triangle) and after (circle) bacterial transfer from mice treated with saline (left) or BFT (right) (n = 8). (D) Cecum weight of recipient mice. (E) qPCR for inflammatory gene expressions in the epididymal adipose tissue of recipient mice (n = 8). *p < 0.05 and **p < 0.01, by unpaired, 2-tailed t test.