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. 2020 Mar 26;15:63. doi: 10.1186/s11671-020-3289-z

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© The Author(s). 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Inhibition effects and survival curve of BEZ235 or BEZ235-loaded NPs administration. a Inhibition effects of BEZ235 or BEZ235-loaded NPs at different concentrations and administered for 24 h in the HepG2 cell line. b Survival curve of BEZ235 or BEZ235-loaded NPs administration. Each value represents the mean ± SD of three independent experiments. *p < 0.05, **p < 0.01 versus BEZ235, NP-BEZ235, or control group