Figure 4.

Primary keratinocytes derived from TG neonatal skin are less migratory and proliferative than those from WT controls. (a) qPCR analysis on Sufu in primary epidermal keratinocytes of NTG and NWT control mice and 7-week-old TG and WT control mice. (b) Proliferation analysis of keratinocytes in TG and WT fibroblasts at 24 and 48 h. (c) Scratch wound experiments of primary keratinocytes of TG mice and controls. All values are expressed as mean ± standard deviation from three different independent experimental sets. *p < 0.05; **p < 0.01; ***p < 0.001. NTG, neonatal TG; NWT, neonatal WT; qPCR; Sufu, suppressor of fused; TG, transgenic; WT, wild type. Color images are available online.