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. 2020 Mar 19;9(5):245–263. doi: 10.1089/wound.2019.0967

Figure 4.

Figure 4.

Illustration showing the application of ROS ratiometric probe on open infection wounds in a murine model. None, Medium, and High indicate various amounts of bacteria administered onto open wounds. The fluorescent, chemiluminescent, and superimposed images reflect the amounts of administered probes, ROS activities, and ratiometric ROS activities, respectively. The overall results show that, with the same amounts of probes administered, increase administered bacteria numbers intensify ratiometric ROS signals. ROS, reactive oxygen species.