Table 1.

Physiological variables at baseline and 30, 60, and 90 min after last it injection

Time, min	ACSF	5-HT2A	5-HT7
$\text{P}{\text{a}}_{\text{C}\text{O}}{}_{{}_2}$
Baseline	43.2 ± 3.6	46.7 ± 8.5	43.6 ± 3.1
30	42.9 ± 3.6	45.6 ± 8.5	43.7 ± 3.4
60	43.4 ± 3.1	43.8 ± 5.4	44.0 ± 3.3
90	42.7 ± 2.9	44.9 ± 9.7	44.4 ± 4.1
$\text{P}{\text{a}}_{\text{O}}{}_{{}_2}$
Baseline	274 ± 66	292 ± 26	303 ± 15
30	264 ± 65	290 ± 22	304 ± 21
60	264 ± 66	277 ± 23	293 ± 19
90	255 ± 59	281 ± 26	289 ± 17
MAP, mmHg
Baseline	129 ± 16	121 ± 7	132 ± 19
30	125 ± 20	122 ± 9	126 ± 21
60	129 ± 22	128 ± 12	131 ± 23
90	136 ± 17	130 ± 8	121 ± 28
pH
Baseline	7.39 ± 0.01	7.36 ± 0.04	7.40 ± 0.02
30	7.40 ± 0.04	7.41 ± 0.05	7.40 ± 0.03
60	7.39 ± 0.03	7.41 ± 0.03	7.39 ± 0.03
90	7.39 ± 0.04	7.40 ± 0.05	7.39 ± 0.03
sBE
Baseline	1.3 ± 1.7	1.0 ± 2.3	2.0 ± 1.5
30	1.7 ± 1.7	3.7 ± 2.3	2.0 ± 0.9
60	1.5 ± 1.3	3.0 ± 2.0	1.9 ± 0.9
90	0.7 ± 1.6	2.6 ± 2.1	1.6 ± 0.7
Temperature, °C
Baseline	37.4 ± 0.8	37.2 ± 0.4	37.5 ± 0.5
30	37.6 ± 0.8	37.3 ± 0.2	37.1 ± 0.3
60	37.7 ± 0.7	37.4 ± 0.7	37.3 ± 0.4
90	37.6 ± 0.7	37.2 ± 0.2	37.6 ± 0.3

ACSF, artificial cerebrospinal fluid; 5-HT_2A, serotonin type 2A receptor; 5-HT₇, serotonin 7 receptor; MAP, mean arterial pressure; sBE, standard base excess.