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. 2020 Jan 23;128(3):523–533. doi: 10.1152/japplphysiol.00546.2019

Table 2.

Physiological variables at baseline and 30, 60, and 90 min after last it injection

Time, min 2-DG + ACSF 2-DG + 5-HT2A 2-DG + 5-HT7 2-DG/cC + 5-HT7
PaCO2
    Baseline 43.9 ± 3.4 40.8 ± 1.7 43.0 ± 3.8 43.0 ± 2.9
    30 43.7 ± 4.2 40.4 ± 2.1 43.8 ± 3.3 43.4 ± 3.4
    60 44.6 ± 3.0 42.8 ± 1.3 43.0 ± 3.2 43.8 ± 3.2
    90 44.8 ± 3.4 40.7 ± 1.3 43.5 ± 3.0 43.3 ± 3.7
PaO2
    Baseline 314 ± 20 304 ± 36 311 ± 27 319 ± 20
    30 302 ± 21 280 ± 58 296 ± 23 319 ± 21
    60 298 ± 42 282 ± 53 292 ± 31 312 ± 20
    90 304 ± 29 267 ± 42 292 ± 35 305 ± 18
MAP, mmHg
    Baseline 138 ± 8 127 ± 28 122 ± 18 124 ± 10
    30 136 ± 12 129 ± 25 118 ± 20 117 ± 13
    60 135 ± 14 130 ± 24 120 ± 19 116 ± 15
    90 133 ± 23 127 ± 24 119 ± 19 108 ± 17
pH
    Baseline 7.38 ± 0.02 7.41 ± 0.03 7.39 ± 0.03 7.39 ± 0.03
    30 7.38 ± 0.04 7.41 ± 0.02 7.40 ± 0.02 7.40 ± 0.03
    60 7.38 ± 0.03 7.41 ± 0.02 7.40 ± 0.02 7.39 ± 0.04
    90 7.38 ± 0.02 7.39 ± 0.05 7.43 ± 0.13 7.39 ± 0.03
sBE
    Baseline 0.7 ± 1.1 1.3 ± 1.5 1.1 ± 1.1 1.2 ± 1.8
    30 0.8 ± 1.8 0.9 ± 1.9 2.3 ± 1.0 1.9 ± 0.9
    60 1.0 ± 1.3 1.7 ± 1.7 1.6 ± 1.0 1.8 ± 1.5
    90 0.9 ± 1.5 0.6 ± 1.6 1.1 ± 1.4 1.2 ± 1.5
Temperature, °C
    Baseline 37.9 ± 0.3 37.3 ± 0.5 37.4 ± 0.4 37.5 ± 0.5
    30 38.0 ± 0.4 37.4 ± 0.6 37.4 ± 0.4 37.2 ± 0.5
    60 37.9 ± 0.6 37.4 ± 0.4 37.5 ± 0.4 37.1 ± 0.5
    90 38.0 ± 0.6 37.3 ± 0.4 37.5 ± 0.4 37.2 ± 0.6

2-DG, 2-deoxyglucose; cC, compound C; ACSF, artificial cerebrospinal fluid; 5-HT2A, serotonin type 2A receptor; 5-HT7, serotonin 7 receptor; MAP, mean arterial pressure; sBE, standard base excess.